Clinical data converge into a mosaic of evidence: core, adjacent and surrounding. Life cycle management is best executed with a cross-functional gameplan.
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Core scientific narratives are built by a variety of published data that can be orchestrated to define the impact and demonstrate the differentiation of a novel medicine or diagnostic.

We listen to leading academics and co-create integrated evidence. Our plans define what we have and what we need to substantiate our ambition. Cross-functional groups and external academic partners contribute to this mosaic. Having a guiding star to follow is critical; building a picture is a matter of choreographing data.

If we take the image of a tree, preclinical and translational work are the roots. The trunk is the pivotal trial knowledge. The branches represent indication expansion trials. The leaves are smaller pieces of investigator-initiated studies, real world platform data and outcomes. Research serves to substantiate the impact of a medicine or diagnostic. Crowdfunding solutions can be a way to build up global data platforms answering core clinical questions and connecting investigators around the world engaged in concerted clinical research.
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Research is a team sport. Co-creating an ambition by defining the main research questions means bringing together experts from different disciplines. They generate the data needed by the complementary stakeholders: physicians, patients, payers, the academic community. Being able to integrate and summarize all these different pieces into a mosaic of information demonstrates how knowledge is advancing when is drug or diagnostic product is being developed. Investigators come together on a data platform to answer critical clinical questions. We can observe the impact of the right international research initiatives when fewer individual research proposals are being proposed, as the data platforms bringing investigators together have the potential to build consortia and academic partnerships with a much greater impact than small individual studies.
A mosaic tree
Integrated evidence plans are mosaics combining individual research work into an overarching whole: the strategic narrative. A mosaic tree further distinguishes the weight of the data: roots, trunk, branches and leaves.
“To build integrated evidence you have to plan a highly creative process that repeats the ambition in every aspect. You define the tiles and put them together to form a larger overarching mosaic uniting all stakeholders, both internal and external.”
Dr. Nicole Selenko-Gebauer
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Dr. Nicole Selenko-Gebauer